Read e-book online Burger's Medicinal Chemistry and Drug Discovery, Vol. 2: PDF

By Donald J. Abraham (ed.)

ISBN-10: 0471370282

ISBN-13: 9780471370284

This new quantity includes severe new chapters on Combinational Chemistry and a number of Parallel Synthesis, excessive Throughput Pharmacology, and Retrometabolism-Based Drug layout and concentrating on.

Show description

Read Online or Download Burger's Medicinal Chemistry and Drug Discovery, Vol. 2: Drug Discovery and Drug Development PDF

Best pharmacy books

Fischer Cancer Chemotherapy Handbook by David S. Fischer, Henry J. Durivage, M. Tish Knobf, Nancy PDF

Here is a entire, but compact and useful advisor to the care and chemotherapeutic remedy of melanoma sufferers. It encompasses all significant chemotherapeutic brokers and combos, investigational and newly licensed medications, and describes their mechanisms of motion, symptoms, metabolism, dose, management, toxicity, and drug interactions and incompatibilities.

Get MCQs in Pharmacy Practice, 2nd Edition PDF

This booklet is designed as a revision relief, and covers themes usually featured in pharmacy undergraduate registration and licensing a number of selection examinations. This e-book is a perfect revision advisor for these getting ready to take a seat a a number of selection Questions (MCQs) exam in pharmacy. It covers universal common pharmacy perform interventions and operations and different issues generally featured in examinations resembling easy pharmaceutical calculations, doses, strengths, nomenclature, abbreviations, dosage types, specialties, alternate and universal names, biochemical assessments, type, side-effects, and customary illnesses.

Gene Profiles in Drug Design by Brett A. Lidbury, Suresh Mahalingam PDF

With the winning mapping of the human genome, now we have entered an age of extraordinary chance within which researchers are commencing to follow this massive repository of information to the remedy of human disorder. Gene-profiling applied sciences and the idea that of individualized medication are resulting in the improvement of gear with more advantageous specificity.

Foundation in Pharmacy Practice - download pdf or read online

This can be an introductory assessment to pharmacy perform. This introductory evaluate to pharmacy perform is vital for first yr undergraduate scholars, supplying an summary of the crucial pharmacy perform subject matters in a pragmatic and succinct demeanour. The textual content presents a place to begin for additional examine and is facilitated by means of ordinary signposting and referencing to express texts.

Extra info for Burger's Medicinal Chemistry and Drug Discovery, Vol. 2: Drug Discovery and Drug Development

Example text

31. Illustration of fluorous phase methods in the synthesis of a mappacine library. One is disturbed to note also that in a few cases where a census has been taken of very large libraries, the wrong or missing structures are not statistically distributed (149). Thus, such libraries have a structural bias. For example, the chemistry may selectively favor production of more lipophilic substances so that hydrophilic examples are underrepresented. It is hard to see how to get around this conveniently.

Frank, P. V . Devasthale, E. J. Gentry, V . T . Ravikumar, A. , Comb. Chem. , 1, 89 (1998). 131. C. S. Lee, D. Allwine,M. R. Barbachyn, K. C. Grega, L. A. , Biorg. Med. , 9, 3243 (2001). 132. M. F. Gordeev, Curr. Opin. Drug Discov. , 4,450 (2001). 133. S. C. Bergmeier and S. J. Katz, J. Comb. , 4, 162 (2002). 134. M. Kidwai, P. Misra, K. R. Bhushan, R. K. Saxena, and M . Singh, Monatsh. , 131,937 (2000). 135. C. Zhang, S. Sarshar, E. J. Moran, S. Krane, J. C. Rodarte, K. D. , Biorg. Med. Chem. , 10,2603 (2000).

Acad. Sci. USA, 96,4330 (1999). 106. J . Jiracek, A. Yiotakis, B. Vincent, B. Checler, and V . Dive, J. Biol. , 271, 19606 (1996). 107. M. Bastos, N. J. Maeji, and R. H. Abeles, Proc. Natl. Acad. Sci. USA, 92,6738 (1995). 108. J. M . Salvino, R. Mathew, T . Kiesow, R. Narensingh, H. J. , Biorg. Med. Chem. , 10, 1637 (2000). 109. S. M. Dankwaardt, R. J. Billedeau, L. K. Lawley, S. C. Abbot, R. L. , Biorg. Med. Chem. , 10, 2513 (2000). 110. T. A. Rano, T . Timkey, E. P. Peterson, J . Rotonda, D. W .

Download PDF sample

Burger's Medicinal Chemistry and Drug Discovery, Vol. 2: Drug Discovery and Drug Development by Donald J. Abraham (ed.)

by Joseph

Rated 4.60 of 5 – based on 42 votes