By Alexander Kohn (auth.), Alexander Kohn, Adam Shatkay (eds.)
The OHOLO meetings were convened every year from the Spring of 1956; the huge components they've got coated, from diverse and overlapping disciplines, should be obvious from the next checklist: 1956 Bacterial Genetics (not released) 1957 Tissue Cultures in Virological study (not released) 1958 Inborn and bought Resistance to an infection in Animals (not released) 1959 Experimental method of psychological illnesses (not released) 1960 Cryptobiotic levels in organic platforms* 1961 Virus-Cell Relationships** 1962 organic Synthesis and serve as of Nucleic Acids** 1963 mobile keep watch over Mechanism of Macromolecular Synthesis** 1964 Molecular facets of Immunology** 1965 phone Surfaces** 1966 Chemistry and Biology of Psychotropic brokers (not released) 1967 constitution and Mode of motion of Enzymes** 1968 development and Differentiation of Cells In Vitro** 1969 Behaviour of Animal Cells in Culture** 1970 Microbial Toxins** 1971 interplay of Chemical brokers with Cholinergic Mechanisms** 1972 Immunity in Viral and Rickettsial Diseases*** The members who attend those meetings are drawn from dif ferent medical associations in Israel and from many overseas nations; they're engaged in fields of analysis which signify largely divergent methods to biology. hence a distinguishing function of the OHOLO conferences has been their multi-disciplinary nature. released by way of Elsevier Publishing Co. , Amsterdam (1960). * ** released by way of the Israel Institute for organic study, Ness Ziona. *** released through Plenum Press, manhattan (1972). ix PREFACE x those small foreign meetings also are characterised by means of their comfy surroundings, with abundant time for casual in addition to formal discussions.
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The most plausible interpretation of these structures is~hat they are transcription complexes with growing RNA chains which have been labeled during the 3H] uridine pulse. e. in partially relaxed transcription complexes, the nascent chains were preferentially associated with the relaxed portion of the circle, suggests that the physiological process goes from the twisted to the relaxed form. Each local unwinding of the DNA duplex, necessary for initiation and propagation of transcription, would produce a partial relaxation of the original supercoiled structure, until, for a sufficient number of initiation points, the superhelical density would become zero.
BECKMANN, S. SARID, J. GRIMBERG, M. 2. LITTAUER. (1971) P40C. Natt. Se£. USA, 68, 2268. SYMMETRICAL TRANSCRIPTION IN ANIMAL CELLS AND VIRUSES Yosef Aloni Department of Genetics, Weizmann Institute of Science Rehovot, Israel INTRODUCTION I would like to discuss the first step of genetic transfer, that from DNA to RNA, namely the transcription process. It is assumed that there is a selectivity in transcription; thus, not all the genetic information of the DNA is transcribed to RNA; there is transcription of only portions of certain DNA templates and non-transcription of others.
To resolve between these alternatives, RNA labeled at early outgrowth was eluted from the filters and rehybridized to B. cereus or CP-Sl phage DNA. While 50 percent of the label rehybrldized to CP-Sl DNA, only 2 percent hybridized to B. cereus DNA, confirming there is a low rate of phage RNA synthesis before the increase observed at 4S min. If early outgrowth proteins are required for phage DNA transcription, inhibition of protein synthesis will result in the elimination of the increase in rate of phage RNA synthesis at 45 min.
Control of Gene Expression by Alexander Kohn (auth.), Alexander Kohn, Adam Shatkay (eds.)