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By Alexander von Muralt (auth.)

ISBN-10: 3540016260

ISBN-13: 9783540016267

ISBN-10: 3540369694

ISBN-13: 9783540369691

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15. T h e d u a l e f f e c t s , e x c i t a t o r y a n d d e p r e s s i n g ot t h e c a t h o d e a n d a n o d e . . 16. The cocmponents of the membrane potential changes . . . . . 17. T h e o s c i l l a t o r y c h a r a c t e r of t h e l o c a l r e s p o n s e s . . . . . . . . 18. T h e r e l a t i o n s b e t w e e n l o c a l r e s p o n s e s a n d t h e s p i k e p o t e n t i a l . . . . 19. T h e i n i t i a t i o n o f n e r v e i m p u l s e s . . . . . .

In Wirklichkeit findet aber schon unterhalb der Schwelle eine Reaktion statt, die W~rme produziert. Die Ziindtemperatur witre dadurch charakterisiert, dab bei ihr die W~rmeproduktion gleich der Witrmeabgabe an die kiihlere Umgebung ist. Der Durchgang der IZurve durch Null bedeutet also die Ziindtemperatur oder ffir uns die Schwelle. Es ist der Wert 0~,Z" von x, des ,,Aktivitittsgrades" d~ oder: des ,,6tat d'excitation", bei dem der Zustand labil wird und bei dessen 13berschreiten, wenn dx/dt positiv wird, der ProzeB tawinenartig anwitchst.

2. T h e c a t h o d a l local r e s p o n s e . a) Brief stimuli. The first convincing evidence for the development of a local response at the cathode of subthreshold brief stimuli was given by HODGKIN in t938. He showed that, in isolated single fibers from Carcinus maenas, if such shocks are applied, the records from the cathode to a distant point in the fiber differ significantly from the records from the anode, obtained u ~on reversal of the polarity of the stimuli. As shown in fig. t, the two records H are not mirror images; the negativity at the cathode may exceed I/ importantly the positivity that develops at the anode.

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Ergebnisse der physiologie biologischen chemie und experimentellen pharmakologie by Alexander von Muralt (auth.)


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